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The antibody against BRF1 was raised in rabbit using the Synthesized peptide derived from internal of Human TF3B. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against BRF1 was raised in rabbit using the Synthesized peptide derived from internal of Human TF3B. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
$297.00
Western blot analysis of extracts from HeLa cells and Jurkat cells, using TF3B antibody.
Immunohistochemistry analysis of paraffin-embedded human brain tissue using TF3B antibody.2
Immunofluorescence analysis of MCF-7cells, using TF3B antibody.3
| Cat.No | ADC-41851A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BRF1 |
| Target Synonyms | 90kD antibody; TF3B_HUMAN antibody; TF3B90 antibody; TFIIIB90 antibody; Transcription factor IIIB 90 kDa subunit antibody; Transcription initiation factor IIIB antibody, B related factor 1 antibody; B-related factor 1 antibody; BRF antibody; BRF-1 antibody; brf1 antibody; BRF1 homolog, GTF3B subunit 2 antibody; TATA box-binding protein-associated factor antibody; TBP associated factor, RNA polymerase III, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) antibody; General transcription factor IIIB | Form | Liquid |
| Species Reactivity | Human, Mouse | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human TF3B. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q92994 |
Uniprot Id
Q92994
Target Species
Human
Target Name
BRF1
Target Full Name
Transcription factor IIIB 90 kDa subunit
Target Function
General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.
Target Involvement
Cerebellofaciodental syndrome (CFDS)
Target Subcellular Location
Nucleus.
Target Protein Families
TFIIB family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
B related factor 1; B-related factor 1; BRF; BRF-1; brf1; BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae); General transcription factor IIIB, 90kD subunit; GTF3B; hBRF; hTFIIIB90; RNA polymerase III; subunit 2; TAF3B2; TAF3C; TAFIII90; TATA box binding protein (TBP) associated factor 3C; TATA box binding protein (TBP) associated factor, RNA polymerase III, GTF3B subunit 2; TATA box-binding protein-associated factor; TBP associated factor, RNA polymerase III, 90kD; TF3B_HUMAN; TF3B90; TFIIIB90; Transcription factor IIIB 90 kDa subunit; Transcription initiation factor IIIB
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