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The antibody against BRINP1 was raised in rabbit using the Recombinant Human BMP/retinoic acid-inducible neural-specific protein 1 protein (20-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against BRINP1 was raised in rabbit using the Recombinant Human BMP/retinoic acid-inducible neural-specific protein 1 protein (20-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human brain tissue using BRINP1 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using BRINP1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-22140A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BRINP1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human BMP/retinoic acid-inducible neural-specific protein 1 protein (20-320AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O60477 |
Uniprot Id
O60477
Target Species
Human
Target Name
BRINP1
Target Full Name
BMP/retinoic acid-inducible neural-specific protein 1
Target Function
Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway.
Target Subcellular Location
Cytoplasm.
Target Protein Families
BRINP family
Target Tissue Specificity
Highly expressed in brain. Weakly expressed in heart, lung, skeletal muscle, kidney, thymus, prostate, testis and small intestine.
Target Synonyms
BMP/retinoic acid-inducible neural-specific protein 1; BRINP1; DBC1; DBC1_HUMAN; DBCCR1 ; Deleted in bladder cancer protein 1; Deleted in bladder cancer protein 1 precursor; FAM5A; IB3089A; Protein FAM5A
Target Background
This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.
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