Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against BSND was raised in rabbit using the Recombinant Human Barttin protein (54-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against BSND was raised in rabbit using the Recombinant Human Barttin protein (54-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human breast cancer using BSND Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using BSND Antibody at dilution of 1:1002
| Cat.No | ADC-43863A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BSND |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Barttin protein (54-320AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WZ55 |
Uniprot Id
Q8WZ55
Target Species
Human
Target Name
BSND
Target Full Name
Barttin
Target Function
Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.
Target Involvement
Bartter syndrome 4A, neonatal, with sensorineural deafness (BARTS4A)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cytoplasm.
Target Tissue Specificity
Expressed primarily in kidney. Expressed in specific nephron segments and in the stria vascularis of the inner ear.
Target Synonyms
BART ; Bartter syndrome infantile with sensorineural deafness; Bartter syndrome; infantile; with sensorineural deafness (Barttin); Barttin; Bsnd; BSND_HUMAN; deafness; autosomal recessive 73; DFNB 73; DFNB73
Target Background
This gene encodes an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this gene have been associated with Bartter syndrome with sensorineural deafness.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
