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The antibody against BTD was raised in rabbit using the Recombinant Human Biotinidase protein (322-397AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against BTD was raised in rabbit using the Recombinant Human Biotinidase protein (322-397AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-06148A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BTD |
| Target Synonyms | Biotinase antibody; Biotinidase antibody; Btd antibody; BTD_HUMAN antibody; EC 3.5.1.12 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Biotinidase protein (322-397AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P43251 |
Uniprot Id
P43251
Target Species
Human
Target Name
BTD
Target Full Name
Biotinidase
Target Function
Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.
Target Involvement
Biotinidase deficiency (BTD deficiency)
Target Subcellular Location
Secreted, extracellular space.
Target Protein Families
Carbon-nitrogen hydrolase superfamily, BTD/VNN family
Target Research Area
Metabolism
Target Synonyms
Biotinase; Biotinidase; Btd; BTD_HUMAN; EC 3.5.1.12
Target Background
The protein encoded by this gene functions to recycle protein-bound biotin by cleaving biocytin (biotin-epsilon-lysine), a normal product of carboxylase degradation, resulting in regeneration of free biotin. The encoded protein has also been shown to have biotinyl transferase activity. Mutations in this gene are associated with biotinidase deficiency. Multiple transcript variants encoding different isoforms have been described.
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