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The antibody against BTN1A1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-210 of human BTN1A1 (NP_001723.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against BTN1A1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-210 of human BTN1A1 (NP_001723.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01261A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BTN1A1 |
| Target Synonyms | BT; BTN; BTN1; BTN1A1 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse liver, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 27-210 of human BTN1A1 (NP_001723.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | APFDVIGPPEPILAVVGEDAELPCRLSPNASAEHLELRWFRKKVSPAVLVHRDGREQEAEQMPEYRGRATLVQDGIAKGRVALRIRGVRVSDDGEYTCFFREDGSYEEALVHLKVAALGSDPHISMQVQENGEICLECTSVGWYPEPQVQWRTSKGEKFPSTSESRNPDEEGLFTVAASVIIRD | Uniprot ID | Q13410 |
Uniprot Id
Q13410
Target Species
Human
Target Name
BTN1A1
Target Full Name
Butyrophilin subfamily 1 member A1
Target Function
May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Target Subcellular Location
Membrane; Single-pass type I membrane protein. Secreted.
Target Protein Families
Immunoglobulin superfamily, BTN/MOG family
Target Synonyms
BT; BT1A1_HUMAN; BTN; BTN1; Btn1a1; butyrophilin; Butyrophilin subfamily 1 member A1; butyrophilin; subfamily 1; member A1
Target Background
Butyrophilin is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families
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