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The antibody against BTN3A3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 510-584 of human BTN3A3 (NP_008925.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against BTN3A3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 510-584 of human BTN3A3 (NP_008925.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05761A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BTN3A3 |
| Target Synonyms | BTF3; BTN3.3; BTN3A3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Jurkat, Mouse liver, Mouse spleen, Raji, Rat spleen | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 510-584 of human BTN3A3 (NP_008925.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | TICPIPKEVESSPDPDLVPDHSLETPLTPGLANESGEPQAEVTSLLLPAHPGAEVSPSATTNQNHKLQARTEALY | Uniprot ID | O00478 |
Uniprot Id
O00478
Target Species
Human
Target Name
BTN3A3
Target Full Name
Butyrophilin subfamily 3 member A3
Target Function
Plays a role in T-cell responses in the adaptive immune response.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Immunoglobulin superfamily, BTN/MOG family
Target Tissue Specificity
Detected in peripheral blood mononuclear cells and in T-cells (at protein level). Detected in spleen and lymphocytes.
Target Research Area
Cardiovascular
Target Synonyms
BT3A3_HUMAN; BTF3; BTN3A3; Butyrophilin subfamily 3 member A3
Target Background
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).
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