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The antibody against C12orf65 was raised in rabbit using the Recombinant Human Probable peptide chain release factor C12orf65, mitochondrial protein (36-166AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against C12orf65 was raised in rabbit using the Recombinant Human Probable peptide chain release factor C12orf65, mitochondrial protein (36-166AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human colon cancer using C12orf65 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using C12orf65 Antibody at dilution of 1:1002
| Cat.No | ADC-14958A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | C12orf65 |
| Target Synonyms | C12orf65 antibody; My030Probable peptide chain release factor C12orf65 antibody; mitochondrial antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Probable peptide chain release factor C12orf65, mitochondrial protein (36-166AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H3J6 |
Uniprot Id
Q9H3J6
Target Species
Human
Target Name
MTRFR
Target Full Name
Mitochondrial translation release factor in rescue
Target Function
Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation. As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue.
Target Involvement
Combined oxidative phosphorylation deficiency 7 (COXPD7); Spastic paraplegia 55, autosomal recessive (SPG55)
Target Subcellular Location
Mitochondrion.
Target Protein Families
Prokaryotic/mitochondrial release factor family
Target Tissue Specificity
Expressed in all areas of the brain tested.
Target Synonyms
C12orf65; My030Probable peptide chain release factor C12orf65; mitochondrial
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