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The antibody against C19orf10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human C19orf10 (NP_061980.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against C19orf10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human C19orf10 (NP_061980.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-01720A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | C19orf10 |
| Target Synonyms | IL25; IL27; SF20; IL27w; C19orf10; R33729_1; EUROIMAGE1875335 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, A-431, Mouse liver, Rat pancreas | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human C19orf10 (NP_061980.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MAAPSGGWNGVGASLWAALLLGAVALRPAEAVSEPTTVAFDVRPGGVVHSFSHNVGPGDKYTCMFTYASQGGTNEQWQMSLGTSEDHQHFTCTIWRPQGKSYLYFTQFKAEVRGAEIEYAMAYSKAAFERESDVPLKTEEFEVTKTAVAHRPGAFKAELSKLVIVAKASRTEL | Uniprot ID | Q969H8 |
Uniprot Id
Q969H8
Target Species
Human
Target Name
MYDGF
Target Full Name
Myeloid-derived growth factor
Target Function
Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis.
Target Subcellular Location
Secreted. Endoplasmic reticulum-Golgi intermediate compartment. Endoplasmic reticulum. Golgi apparatus.
Target Protein Families
MYDGF family
Target Tissue Specificity
Expressed in eosinophils (at protein level). Expressed in bone marrow cells. Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties.
Target Synonyms
C19orf10; Chromosome 19 open reading frame 10; CS010_HUMAN; EUROIMAGE1875335; IL 25; IL 27; IL-25; IL25; IL27; IL27w; Interleukin 25; Interleukin 27 working designation ; Interleukin-25; Interleukin25; R33729 1; R337291; SF20 ; Stromal cell derived growth factor; Stromal cell derived growth factor SF20; Stromal cell-derived growth factor SF20; Uncharacterized protein C19orf10 precursor; UPF0556 protein C19orf10
Target Background
The protein encoded by this gene was previously thought to support proliferation of lymphoid cells and was considered an interleukin. However, this activity has not been reproducible and the function of this protein is currently unknown.
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