Rabbit anti-Human C1GALT1 Polyclonal Antibody

The antibody against C1GALT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 194-363 of human C1GALT1 (NP_064541.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03294A

Number

Cat.No	ADA-03294A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	C1GALT1
Target Synonyms	C1GALT; T-synthase; C1GALT1	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse kidney	Application	ELISA, WB

Cat.No

ADA-03294A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

C1GALT1

Target Synonyms

C1GALT; T-synthase; C1GALT1

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse kidney

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 194-363 of human C1GALT1 (NP_064541.1).	Target Species	Human
Immunogen Sequence	FGRRFKPYVKQGYMSGGAGYVLSKEALKRFVDAFKTDKCTHSSSIEDLALGRCMEIMNVEAGDSRDTIGKETFHPFVPEHHLIKGYLPRTFWYWNYNYYPPVEGPGCCSDLAVSFHYVDSTTMYELEYLVYHLRPYGYLYRYQPTLPERILKEISQANKNEDTKVKLGNP	Uniprot ID	Q9NS00

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 194-363 of human C1GALT1 (NP_064541.1).

Target Species

Human

Immunogen Sequence

FGRRFKPYVKQGYMSGGAGYVLSKEALKRFVDAFKTDKCTHSSSIEDLALGRCMEIMNVEAGDSRDTIGKETFHPFVPEHHLIKGYLPRTFWYWNYNYYPPVEGPGCCSDLAVSFHYVDSTTMYELEYLVYHLRPYGYLYRYQPTLPERILKEISQANKNEDTKVKLGNP

Uniprot ID

Q9NS00

Background Information

Uniprot Id

Q9NS00
Target Species

Human
Target Name

C1GALT1
Target Full Name

Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Target Function

Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
Target Subcellular Location

Membrane; Single-pass type II membrane protein.
Target Protein Families

Glycosyltransferase 31 family, Beta3-Gal-T subfamily
Target Tissue Specificity

Widely expressed. Highly expressed in kidney, heart, placenta and liver.
Target Synonyms

C1GALT1Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; EC 2.4.1.122; B3Gal-T8; Core 1 O-glycan T-synthase; Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1; Beta-1,3-galactosyltransferase; Core 1 beta1,3-galactosyltransferase 1; C1GalT1; Core 1 beta3-Gal-T1
Target Background

The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.

Rabbit anti-Human C1GALT1 Polyclonal Antibody

Specifications

Immunogen Information

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