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The antibody against C1GALT1 was raised in rabbit using the Recombinant Human Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 protein (34-143AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against C1GALT1 was raised in rabbit using the Recombinant Human Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 protein (34-143AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-05387A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | C1GALT1 |
| Target Synonyms | 3-galactosyltransferase 1 antibody; Beta-1, 3-galactosyltransferase 1 antibody; C1GalT1 antibody; Core 1 beta3-Gal-T1 antibody, 3-galactosyltransferase antibody; Core 1 beta1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 protein (34-143AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NS00 |
Uniprot Id
Q9NS00
Target Species
Human
Target Name
C1GALT1
Target Full Name
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Target Function
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
Target Subcellular Location
Membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase 31 family, Beta3-Gal-T subfamily
Target Tissue Specificity
Widely expressed. Highly expressed in kidney, heart, placenta and liver.
Target Synonyms
C1GALT1Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; EC 2.4.1.122; B3Gal-T8; Core 1 O-glycan T-synthase; Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1; Beta-1,3-galactosyltransferase; Core 1 beta1,3-galactosyltransferase 1; C1GalT1; Core 1 beta3-Gal-T1
Target Background
The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.
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