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The antibody against C2CD5 was raised in rabbit using the Human KIAA0528 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
The antibody against C2CD5 was raised in rabbit using the Human KIAA0528 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
$600.00
| Cat.No | ADC-52950A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | C2CD5 |
| Target Synonyms | C2CD5 antibody; CDP138 antibody; KIAA0528C2 domain-containing protein 5 antibody; C2 domain-containing phosphoprotein of 138 kDa antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Human KIAA0528 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86YS7 |
Uniprot Id
Q86YS7
Target Species
Human
Target Name
C2CD5
Target Full Name
C2 domain-containing protein 5
Target Function
Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.
Target Subcellular Location
Cytoplasmic vesicle membrane. Cytoplasm, cell cortex. Cell membrane. Cell projection, ruffle. Note=Dynamically associated with GLUT4-containing glucose storage vesicles (GSV) and plasma membrane in response to insulin stimulation.
Target Synonyms
C2CD5; CDP138; KIAA0528C2 domain-containing protein 5; C2 domain-containing phosphoprotein of 138 kDa
Target Background
Enables calcium ion binding activity and calcium-dependent phospholipid binding activity. Involved in cellular response to insulin stimulus; intracellular protein transmembrane transport; and positive regulation of transport. Located in several cellular components, including centriolar satellite; cytoplasmic vesicle membrane; and ruffle membrane.
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