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The antibody against C5AR2 was raised in rabbit using the Peptide sequence from Human C5a anaphylatoxin chemotactic receptor 2 protein (2-19AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against C5AR2 was raised in rabbit using the Peptide sequence from Human C5a anaphylatoxin chemotactic receptor 2 protein (2-19AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-02365A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | C5AR2 |
| Target Synonyms | C5AR2; C5L2; GPR77; C5a anaphylatoxin chemotactic receptor 2; Complement component 5a receptor 2; G-protein coupled receptor 77 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Peptide sequence from Human C5a anaphylatoxin chemotactic receptor 2 protein (2-19AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9P296 |
Uniprot Id
Q9P296
Target Species
Human
Target Name
C5AR2
Target Full Name
C5a anaphylatoxin chemotactic receptor 2
Target Function
Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
Frontal cortex, hippocampus, hypothalamus, pons and liver.
Target Synonyms
C5AR2; C5L2; GPR77; C5a anaphylatoxin chemotactic receptor 2; Complement component 5a receptor 2; G-protein coupled receptor 77
Target Background
This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.
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