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The antibody against C6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 586-934 of human C6 (NP_000056.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against C6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 586-934 of human C6 (NP_000056.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01323A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | C6 |
| Target Synonyms | C6 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse liver, Mouse lung, Rat lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 586-934 of human C6 (NP_000056.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P13671 | Immunogen Sequence |
Uniprot Id
P13671
Target Species
Human
Target Name
C6
Target Full Name
Complement component C6
Target Function
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
Target Involvement
Complement component 6 deficiency (C6D)
Target Subcellular Location
Secreted.
Target Protein Families
Complement C6/C7/C8/C9 family
Target Synonyms
AW111623; C6; CO6_HUMAN; Complement component 6; Complement component C6
Target Background
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.
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