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The antibody against C8A was raised in rabbit using the Recombinant Human Complement component C8 alpha chain protein (310-460AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against C8A was raised in rabbit using the Recombinant Human Complement component C8 alpha chain protein (310-460AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human liver tissue using C8A Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer using C8A Antibody at dilution of 1:1002
| Cat.No | ADC-16621A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | C8A |
| Target Synonyms | alpha polypeptide antibody; Complement component C8 alpha chain antibody, C8A antibody; CO8A_HUMAN antibody; Complement component 8 subunit alpha antibody; Complement component 8 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Complement component C8 alpha chain protein (310-460AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P07357 |
Uniprot Id
P07357
Target Species
Human
Target Name
C8A
Target Full Name
Complement component C8 alpha chain
Target Function
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself.
Target Involvement
Complement component 8 deficiency, 1 (C8D1)
Target Subcellular Location
Secreted. Cell membrane; Multi-pass membrane protein. Note=Secreted as soluble protein. Inserts into the cell membrane of target cells.
Target Protein Families
Complement C6/C7/C8/C9 family
Target Research Area
Immunology
Target Synonyms
C8A; CO8A_HUMAN; Complement component 8 subunit alpha; Complement component 8, alpha polypeptide; Complement component C8 alpha chain
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