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Rabbit anti-Human C9 Polyclonal Antibody

The antibody against C9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-265 of human C9 (NP_001728.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09669A

The antibody against C9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-265 of human C9 (NP_001728.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-09669A ClonalityPolyclonal
Host SpeciesRabbitTarget NameC9
Target SynonymsC9D; ARMD15; C9FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 22-265 of human C9 (NP_001728.1).Target SpeciesHuman
Uniprot IDP02748Immunogen Sequence
Background Information
  • Uniprot Id

    P02748

  • Target Species

    Human

  • Target Name

    C9

  • Target Full Name

    Complement component C9

  • Target Function

    Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.

  • Target Involvement

    Complement component 9 deficiency (C9D); Macular degeneration, age-related, 15 (ARMD15)

  • Target Subcellular Location

    Secreted. Target cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Complement C6/C7/C8/C9 family

  • Target Tissue Specificity

    Plasma (at protein level).

  • Target Research Area

    Immunology

  • Target Synonyms

    C9; Complement component C9

  • Target Background

    This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency.

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