Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against CA12 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-301 of human CA12 (NP_001209.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CA12 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-301 of human CA12 (NP_001209.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01325A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CA12 |
| Target Synonyms | CAXII; CA-XII; T18816; HsT18816; CA12 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HT-29 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 25-301 of human CA12 (NP_001209.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O43570 | Immunogen Sequence |
Uniprot Id
O43570
Target Species
Human
Target Name
CA12
Target Full Name
Carbonic anhydrase 12
Target Function
Reversible hydration of carbon dioxide.
Target Involvement
Hyperchlorhidrosis, isolated (HCHLH)
Target Subcellular Location
Membrane; Single-pass type I membrane protein. Cell membrane.
Target Protein Families
Alpha-carbonic anhydrase family
Target Tissue Specificity
Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis. Expressed in sweat gl
Target Research Area
Cancer
Target Synonyms
CA 12; CA XII; CA-XII; CA12; CAH12_HUMAN; Carbonate dehydratase XII; Carbonic anhydrase 12; Carbonic anhydrase XII; Carbonic dehydratase; CAXII; FLJ20151; HsT18816; T18816; Tumor antigen HOM RCC 3.1.3; Tumor antigen HOM-RCC-3.1.3
Target Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
