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The antibody against CA3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human CA3 (NP_005172.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against CA3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human CA3 (NP_005172.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-10311A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CA3 |
| Target Synonyms | Car3; CAIII; CA3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse skeletal muscle, Rat liver, Rat spinal cord | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human CA3 (NP_005172.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P07451 | Immunogen Sequence |
Uniprot Id
P07451
Target Species
Human
Target Name
CA3
Target Full Name
Carbonic anhydrase 3
Target Function
Reversible hydration of carbon dioxide.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Alpha-carbonic anhydrase family
Target Tissue Specificity
Muscle specific.
Target Synonyms
CA III ; CA-III; Ca3; CAH3_HUMAN; CAIII ; Car3 ; Carbonate dehydratase III; Carbonic anhydrase 3; Carbonic anhydrase III; Carbonic anhydrase III muscle specific; EC 4.2.1.1; Epididymis secretory sperm binding protein Li 167mP; HEL S 167mP
Target Background
Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns.
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