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The antibody against CACNB2 was raised in rabbit using the Synthetic peptide of Human CACNB2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against CACNB2 was raised in rabbit using the Synthetic peptide of Human CACNB2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-27001A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CACNB2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human CACNB2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q08289 |
Uniprot Id
Q08289
Target Species
Human
Target Name
CACNB2
Target Full Name
Voltage-dependent L-type calcium channel subunit beta-2
Target Function
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Target Involvement
Brugada syndrome 4 (BRGDA4)
Target Subcellular Location
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
Calcium channel beta subunit family
Target Tissue Specificity
Expressed in all tissues.
Target Synonyms
CAB2; MYSB; CAVB2; CACNLB2; CACNB2
Target Background
This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described.
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