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The antibody against CACNB3 was raised in rabbit using the Synthetic Peptide as the immunogen. This antibody exists as a non-conjugated isotype IgG. This antibody has been validated on WB, IHC.
The antibody against CACNB3 was raised in rabbit using the Synthetic Peptide as the immunogen. This antibody exists as a non-conjugated isotype IgG. This antibody has been validated on WB, IHC.
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Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using CACNB3 Polyclonal Antibody.
Western blot analysis of 1) Mouse Brain Tissue, 2) Rat Brain Tissue using CACNB3 Polyclonal Antibody.2
| Cat.No | ADC-33124A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CACNB3 |
| Form | Liquid | Species Reactivity | Mouse, Rat |
| Isotype | IgG | Storage Buffer | PH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS |
| Conjugate | Non-conjugated | Application | IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthetic Peptide | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P54284 |
Uniprot Id
P54284
Target Species
Human
Target Name
CACNB3
Target Full Name
Voltage-dependent L-type calcium channel subunit beta-3
Target Function
Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation. Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Calcium channel beta subunit family
Target Tissue Specificity
Expressed mostly in brain, colon and ovary.
Target Synonyms
CAB3; CACB3_HUMAN; Cacnb3; CACNLB3; Calcium channel voltage dependent beta 3 subunit; Calcium channel voltage-dependent subunit beta 3; FLJ58949; Voltage-dependent L-type calcium channel subunit beta-3
Target Background
This gene encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport.
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