Rabbit anti-Human CADM3 Polyclonal Antibody

The antibody against CADM3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-330 of human CADM3 (NP_001120645.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03882A

Number

Cat.No	ADA-03882A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CADM3
Target Synonyms	BIgR; NECL1; TSLL1; CMT2FF; IGSF4B; Necl-1; synCAM3; CADM3	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, HL-60, MCF7, Mouse brain, U-87MG	Application	ELISA, WB

Cat.No

ADA-03882A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CADM3

Target Synonyms

BIgR; NECL1; TSLL1; CMT2FF; IGSF4B; Necl-1; synCAM3; CADM3

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, HL-60, MCF7, Mouse brain, U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 25-330 of human CADM3 (NP_001120645.1).	Target Species	Human
Uniprot ID	Q8N126	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 25-330 of human CADM3 (NP_001120645.1).

Target Species

Human

Uniprot ID

Q8N126

Immunogen Sequence

Background Information

Uniprot Id

Q8N126
Target Species

Human
Target Name

CADM3
Target Full Name

Cell adhesion molecule 3
Target Function

Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions.
Target Subcellular Location

Cell membrane; Single-pass type I membrane protein. Cell junction.
Target Protein Families

Nectin family
Target Tissue Specificity

Isoform 1 is expressed mainly in adult and fetal brain. Isoform 2 is highly expressed in adult brain and weakly expressed in placenta. In brain, Isoform 2 is highly expressed in cerebellum.
Target Synonyms

BIgR; Brain immunoglobulin receptor; CADM 3; cadm3; CADM3_HUMAN; Cell adhesion molecule 3; Dendritic cell nectin like protein 1 short isoform; FLJ10698; IgSF4B; Immunoglobulin superfamily member 4B; Necl 1; Necl-1; NECL1; Nectin like 1; Nectin like protein 1; Nectin-like protein 1; Synaptic cell adhesion molecule 3; synCAM3; TSLC1 like 1; TSLC1 like protein 1; TSLC1-like protein 1; TSLL1
Target Background

The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene.

Rabbit anti-Human CADM3 Polyclonal Antibody

Specifications

Immunogen Information

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