Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against CADPS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human CADPS2 (NP_001009571.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CADPS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human CADPS2 (NP_001009571.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06012A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CADPS2 |
| Target Synonyms | CAPS2; CADPS2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-431, SGC-7901, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human CADPS2 (NP_001009571.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPSPSVLSEGRDEPQRQLDDEQE | Uniprot ID | Q86UW7 |
Uniprot Id
Q86UW7
Target Species
Human
Target Name
CADPS2
Target Full Name
Calcium-dependent secretion activator 2
Target Function
Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles.
Target Subcellular Location
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Note=Membrane-associated to vesicles. Strongly enriched in synaptic fractions. Probably localizes to different vesicles compared to CADPS. Enriched on vesicular structures in the parallel fiber terminal of granule cells that are distinct from synaptic vesicles.
Target Tissue Specificity
Widely expressed. Expressed in all adult and fetal tissues examined, with the strongest expression in kidney and pancreas. In brain, it is expressed at high levels in cerebellum, to a lesser degree in cerebral cortex, occipital pole, and frontal and tempo
Target Synonyms
CADPS2; CAPS2; KIAA1591Calcium-dependent secretion activator 2; Calcium-dependent activator protein for secretion 2; CAPS-2
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
