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The antibody against CALHM3 was raised in rabbit using the Recombinant Human Calcium homeostasis modulator protein 3 protein (201-350AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against CALHM3 was raised in rabbit using the Recombinant Human Calcium homeostasis modulator protein 3 protein (201-350AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human gastric cancer using CALHM3 Antibody at dilution of 1:1002
| Cat.No | ADC-19507A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CALHM3 |
| Target Synonyms | CALHM3; FAM26A; Calcium homeostasis modulator protein 3; Protein A | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Calcium homeostasis modulator protein 3 protein (201-350AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86XJ0 |
Uniprot Id
Q86XJ0
Target Species
Human
Target Name
CALHM3
Target Full Name
Calcium homeostasis modulator protein 3
Target Function
Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs). CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.
Target Subcellular Location
Basolateral cell membrane; Multi-pass membrane protein.
Target Protein Families
CALHM family
Target Tissue Specificity
Specifically expressed in circumvallate taste bud cells.
Target Synonyms
CALHM3; FAM26A; Calcium homeostasis modulator protein 3; Protein A
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