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The antibody against Calretinin was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-271 of human Calretinin (NP_001731.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against Calretinin was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-271 of human Calretinin (NP_001731.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-10866A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Calretinin |
| Target Synonyms | CR; CAL2; CAB29; Calretinin | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, A-431, HEL, Mouse brain, Rat testis, U2OS | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-271 of human Calretinin (NP_001731.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P22676 | Immunogen Sequence |
Uniprot Id
P22676
Target Species
Human
Target Name
CALB2
Target Full Name
Calretinin
Target Function
Calretinin is a calcium-binding protein which is abundant in auditory neurons.
Target Protein Families
Calbindin family
Target Tissue Specificity
Brain.
Target Synonyms
29 kDa calbindin; CAB 29; CAB29; CAL 2; CAL2; CALB 2; CALB2; CALB2_HUMAN; Calbindin 2 29kDa; Calbindin 2; Calbindin D29K; Calbindin2; Calretinin; CR
Target Background
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants.
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