Rabbit anti-Human Calumenin Monoclonal Antibody

The antibody against Calumenin was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 200-300 of human Calumenin (O43852) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-13455A

Number

Cat.No	ADA-13455A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	Calumenin
Target Synonyms	CALU; calumenin; Calumenin	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	NIH/3T3, HT-29, Mouse testis, Mouse uterus	Application	ELISA, WB, IHC-P

Cat.No

ADA-13455A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

Calumenin

Target Synonyms

CALU; calumenin; Calumenin

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

NIH/3T3, HT-29, Mouse testis, Mouse uterus

Application

ELISA, WB, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Calumenin (O43852).	Target Species	Human
Immunogen Sequence	IDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGS	Uniprot ID	O43852

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Calumenin (O43852).

Target Species

Human

Immunogen Sequence

IDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGS

Uniprot ID

O43852

Background Information

Uniprot Id

O43852
Target Species

Human
Target Name

CALU
Target Full Name

Calumenin
Target Function

Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity.
Target Subcellular Location

Endoplasmic reticulum membrane. Golgi apparatus. Secreted. Melanosome. Sarcoplasmic reticulum lumen.
Target Protein Families

CREC family
Target Tissue Specificity

Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.
Target Synonyms

CALU; CALU_HUMAN; Calumenin 1; Calumenin 2; Calumenin; Crocalbin; crocalbin-like protein; FLJ90608; IEF SSP 9302; multiple EF-hand protein; OTTHUMP00000212712; OTTHUMP00000212713; OTTHUMP00000212714; OTTHUMP00000212715
Target Background

The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.

Rabbit anti-Human Calumenin Monoclonal Antibody

Specifications

Immunogen Information

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