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The antibody against CAMP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 31-170 of human CAMP (NP_004336.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against CAMP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 31-170 of human CAMP (NP_004336.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-08815A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CAMP |
| Target Synonyms | LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39; CAMP | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse spleen, THP-1 | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 31-170 of human CAMP (NP_004336.3). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | IIAQVLSYKEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARGSFDISCDKDNKRFALLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPR | Uniprot ID | P49913 |
Uniprot Id
P49913
Target Species
Human
Target Name
CAMP
Target Full Name
Cathelicidin antimicrobial peptide
Target Function
Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.
Target Subcellular Location
Secreted.
Target Protein Families
Cathelicidin family
Target Tissue Specificity
Expressed in bone marrow and testis and neutrophils.
Target Research Area
others
Target Synonyms
18 kDa cationic antimicrobial protein; Antibacterial peptide LL-37; Antibacterial protein FALL-39; CAMP; CAMP_HUMAN; CAP 18; CAP-18; CAP18; Cathelicidin antimicrobial peptide; Cathelin-like protein; Cathelin-related antimicrobial peptide; CATHL3; Cationic antimicrobial protein; 18-KD; CLP; Cnlp; Cramp; CRAMP; mouse; homolog of; FALL 39 ; FALL-39 peptide antibiotic; FALL39 ; hCAP 18; hCAP-18; hCAP18; HSD26 ; LL37; MCLP; Peptide antibiotic; PR-39; porcine; homolog of
Target Background
This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. The protein plays an important role in innate immunity defense against viruses. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation.
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