Rabbit anti-Human CANT1 Polyclonal Antibody

The antibody against CANT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 62-231 of human CANT1 (NP_620148.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03073A

Number

Cat.No	ADA-03073A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CANT1
Target Synonyms	DBQD; EDM7; DBQD1; SCAN1; SHAPY; SCAN-1; CANT1	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	A-549, HT-29	Application	ELISA, WB

Cat.No

ADA-03073A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CANT1

Target Synonyms

DBQD; EDM7; DBQD1; SCAN1; SHAPY; SCAN-1; CANT1

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

A-549, HT-29

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 62-231 of human CANT1 (NP_620148.1).	Target Species	Human
Immunogen Sequence	HRPAPGRPPTHNAHNWRLGQAPANWYNDTYPLSPPQRTPAGIRYRIAVIADLDTESRAQEENTWFSYLKKGYLTLSDSGDKVAVEWDKDHGVLESHLAEKGRGMELSDLIVFNGKLYSVDDRTGVVYQIEGSKAVPWVILSDGDGTVEKGFKAEWLAVKDERLYVGGLGK	Uniprot ID	Q8WVQ1

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 62-231 of human CANT1 (NP_620148.1).

Target Species

Human

Immunogen Sequence

HRPAPGRPPTHNAHNWRLGQAPANWYNDTYPLSPPQRTPAGIRYRIAVIADLDTESRAQEENTWFSYLKKGYLTLSDSGDKVAVEWDKDHGVLESHLAEKGRGMELSDLIVFNGKLYSVDDRTGVVYQIEGSKAVPWVILSDGDGTVEKGFKAEWLAVKDERLYVGGLGK

Uniprot ID

Q8WVQ1

Background Information

Uniprot Id

Q8WVQ1
Target Species

Human
Target Name

CANT1
Target Full Name

Soluble calcium-activated nucleotidase 1
Target Function

Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis.
Target Involvement

Desbuquois dysplasia 1 (DBQD1); Epiphyseal dysplasia, multiple, 7 (EDM7)
Target Subcellular Location

Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Cell membrane. Note=Processed form: Secreted.
Target Protein Families

Apyrase family
Target Tissue Specificity

Widely expressed.
Target Synonyms

Apyrase; Apyrase homolog; Ca2+ dependent endoplasmic reticulum nucleoside diphosphatase; Calcium activated nucleotidase 1; CANT 1; CANT1; CANT1_HUMAN; Putative MAPK activating protein PM09; Putative MAPK-activating protein PM09; Putative NF kappa B activating protein 107; Putative NF-kappa-B-activating protein 107; SCAN 1; SCAN-1; SHAPY; Soluble Ca activated nucleotidase isozyme 1; Soluble calcium activated nucleotidase 1; Soluble calcium activated nucleotidase SCAN 1; Soluble calcium-activated nucleotidase 1
Target Background

This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.

Rabbit anti-Human CANT1 Polyclonal Antibody

Specifications

Immunogen Information

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