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The antibody against CAPN5 was raised in rabbit using the Recombinant Human Calpain-5 protein (361-640AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
The antibody against CAPN5 was raised in rabbit using the Recombinant Human Calpain-5 protein (361-640AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-43985A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CAPN5 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Calpain-5 protein (361-640AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O15484 |
Uniprot Id
O15484
Target Species
Human
Target Name
CAPN5
Target Full Name
Calpain-5
Target Function
Calcium-regulated non-lysosomal thiol-protease.
Target Involvement
Vitreoretinopathy, neovascular inflammatory (VRNI)
Target Protein Families
Peptidase C2 family
Target Tissue Specificity
Expressed in many tissues. Strong expression in the photoreceptor cells of the retina, with a punctate pattern of labeling over the nuclei and inner segments with less expression along the other segments and outer plexiform layer.
Target Synonyms
ADNIV; Calpain htra 3; Calpain htra-3; Calpain-5; CAN5_HUMAN; CAPN 5; Capn5; nCL 3; nCL-3; New calpain 3; VRNI
Target Background
Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3.
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