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The antibody against CAPN9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 391-690 of human CAPN9 (NP_006606.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CAPN9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 391-690 of human CAPN9 (NP_006606.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06041A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CAPN9 |
| Target Synonyms | GC36; nCL-4; CAPN9 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HL-60, HT-29, Mouse small intestine, Mouse stomach, Rat small intestine, Rat stomach, SGC-7901 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 391-690 of human CAPN9 (NP_006606.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O14815 | Immunogen Sequence |
Uniprot Id
O14815
Target Species
Human
Target Name
CAPN9
Target Full Name
Calpain-9
Target Function
Calcium-regulated non-lysosomal thiol-protease.
Target Protein Families
Peptidase C2 family
Target Tissue Specificity
Expressed predominantly in stomach.
Target Synonyms
Calpain-9; Calpain9; CAN9_HUMAN; CAPN 9; CAPN9; CG36 protein; Digestive tract specific calpain; Digestive tract-specific calpain; GC36; nCL-4; nCL4; New calpain 4; novel calpain large subunit-4; novel calpain large subunit4; OTTHUMP00000035899; OTTHUMP00000035900; Protein CG36
Target Background
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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