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The antibody against CAPN9 was raised in rabbit using the Synthesized peptide derived from internal of Human CAPN9. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against CAPN9 was raised in rabbit using the Synthesized peptide derived from internal of Human CAPN9. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from HuvEc cells, using CAPN9 antibody.
| Cat.No | ADC-41390A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CAPN9 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human CAPN9. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O14815 |
Uniprot Id
O14815
Target Species
Human
Target Name
CAPN9
Target Full Name
Calpain-9
Target Function
Calcium-regulated non-lysosomal thiol-protease.
Target Protein Families
Peptidase C2 family
Target Tissue Specificity
Expressed predominantly in stomach.
Target Synonyms
Calpain-9; Calpain9; CAN9_HUMAN; CAPN 9; CAPN9; CG36 protein; Digestive tract specific calpain; Digestive tract-specific calpain; GC36; nCL-4; nCL4; New calpain 4; novel calpain large subunit-4; novel calpain large subunit4; OTTHUMP00000035899; OTTHUMP00000035900; Protein CG36
Target Background
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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