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The antibody against CAPRIN2 was raised in rabbit using the Peptide sequence from Human Caprin-2 protein (83-100AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, Antigen affinity purified.
The antibody against CAPRIN2 was raised in rabbit using the Peptide sequence from Human Caprin-2 protein (83-100AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, Antigen affinity purified.
$299.00
| Cat.No | ADC-01482A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CAPRIN2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | Antigen affinity purified | Conjugate | FITC conjugated |
| Storage | Upon receipt |
| Immunogen Description | Peptide sequence from Human Caprin-2 protein (83-100AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6IMN6 |
Uniprot Id
Q6IMN6
Target Species
Human
Target Name
CAPRIN2
Target Full Name
Caprin-2
Target Function
Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway. Facilitates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling. May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis.
Target Subcellular Location
[Isoform 1]: Cytoplasm.; [Isoform 2]: Mitochondrion. Cytoplasm. Note=Expressed throughout the cytoplasm.; [Isoform 5]: Mitochondrion. Note=Colocalizes with aggregated mitochondria.; Cell membrane; Peripheral membrane protein.
Target Protein Families
Caprin family
Target Tissue Specificity
Detected in all tissues tested with highest levels of expression in brain and spleen.
Target Synonyms
C1q domain-containing protein 1; C1QDC1; CAPR2_HUMAN; Caprin family member 2; Caprin-2; caprin2; Cytoplasmic activation/proliferation-associated protein 2; EEG 1; EEG1; Gastric cancer multidrug resistance-associated protein; KIAA1873; Protein EEG-1; RNA granule protein 140; RNG140
Target Background
The protein encoded by this gene may regulate the transport of mRNA. It may play a role in the differentiation of erythroblasts. Multiple transcript variants encoding different isoforms have been found for this gene.
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