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The antibody against CAPZA1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human CAPZA1 (NP_006126.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CAPZA1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human CAPZA1 (NP_006126.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04070A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CAPZA1 |
| Target Synonyms | CAPZ; CAZ1; CAPPA1; CAPZA1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse kidney, HL-60, Jurkat, MCF7, Mouse brain, Mouse lung, Rat lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human CAPZA1 (NP_006126.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P52907 | Immunogen Sequence |
Uniprot Id
P52907
Target Species
Human
Target Name
CAPZA1
Target Full Name
F-actin-capping protein subunit alpha-1
Target Function
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions.
Target Subcellular Location
Cytoplasm, cytoskeleton.
Target Protein Families
F-actin-capping protein alpha subunit family
Target Synonyms
Cap Z; Cappa 1; Cappa1; Capping protein (actin filament) muscle Z line alpha 1; Capping protein alpha 1; Capping protein muscle Z line alpha 1; CapZ alpha 1; CapZ alpha-1; CAPZ; CAPZA 1; Capza1; CAZ 1; CAZ1; CAZA1_HUMAN; F actin capping protein alpha 1 subunit; F-actin-capping protein subunit alpha-1
Target Background
CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments.
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