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The antibody against CARMIL1 was raised in rabbit using the Recombinant Human F-actin-uncapping protein LRRC16A protein (1184-1295AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against CARMIL1 was raised in rabbit using the Recombinant Human F-actin-uncapping protein LRRC16A protein (1184-1295AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
$299.00
| Cat.No | ADC-04068A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CARMIL1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF | Storage | Upon receipt |
| Immunogen Description | Recombinant Human F-actin-uncapping protein LRRC16A protein (1184-1295AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5VZK9 |
Uniprot Id
Q5VZK9
Target Species
Human
Target Name
CARMIL1
Target Full Name
F-actin-uncapping protein LRRC16A
Target Function
Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments. Plays a role in lamellipodial protrusion formations and cell migration.
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane. Cell projection, lamellipodium.
Target Protein Families
CARMIL family
Target Tissue Specificity
Expressed in lung, placenta, small intestine, liver, thymus, colon, skeletal muscle, heart and brain. Higher expression in kidney.
Target Synonyms
Acan 125; Capping protein; Arp2/3; and myosin I linker; CARMIL homolog; leucine rich repeat containing 16; Leucine-rich repeat-containing protein 16A; LR16A_HUMAN; Lrrc16 protein; LRRC16A; p116
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