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Rabbit anti-Human CCDC6 Polyclonal Antibody, Biotin conjugated

The antibody against CCDC6 was raised in rabbit using the Recombinant Human Coiled-coil domain-containing protein 6 protein (347-440AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-03305A

The antibody against CCDC6 was raised in rabbit using the Recombinant Human Coiled-coil domain-containing protein 6 protein (347-440AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-03305A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCCDC6
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateBiotin conjugated
ApplicationELISAStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Coiled-coil domain-containing protein 6 protein (347-440AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ16204
Background Information
  • Uniprot Id

    Q16204

  • Target Species

    Human

  • Target Name

    CCDC6

  • Target Full Name

    Coiled-coil domain-containing protein 6

  • Target Involvement

    A chromosomal aberration involving CCDC6 is found in papillary thyroid carcinomas (PTCs). Inversion inv(10)(q11.2;q21) generates the RET/CCDC6 (PTC1) oncogene.

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, cytoskeleton. Note=May be a cytoskeletal protein.

  • Target Tissue Specificity

    Ubiquitously expressed.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    CCDC 6; CCDC6; CCDC6_HUMAN; Coiled coil domain containing 6; Coiled coil domain containing protein 6; Coiled-coil domain-containing protein 6; D10S170; FLJ32286; H4; Papillary thyroid carcinoma encoded protein; Papillary thyroid carcinoma-encoded protein; Protein H4; PTC; TPC; TST 1; TST1

  • Target Background

    This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.

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