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The antibody against CCDC8 was raised in rabbit using the Recombinant Human Coiled-coil domain-containing protein 8 protein (214-513AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against CCDC8 was raised in rabbit using the Recombinant Human Coiled-coil domain-containing protein 8 protein (214-513AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
Immunofluorescent analysis of Hela cells using CCDC8 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
| Cat.No | ADC-14959A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CCDC8 |
| Target Synonyms | CCDC8 antibody; CCDC8_HUMAN antibody; Coiled coil domain containing 8 antibody; Coiled-coil domain-containing protein 8 antibody; DKFZp564K0322 antibody; ENSMUSG00000041117 antibody; MGC72567 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Coiled-coil domain-containing protein 8 protein (214-513AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H0W5 |
Uniprot Id
Q9H0W5
Target Species
Human
Target Name
CCDC8
Target Full Name
Coiled-coil domain-containing protein 8
Target Function
Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Required for localization of CUL7 to the centrosome.
Target Involvement
3M syndrome 3 (3M3)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Target Tissue Specificity
Widely expressed with low levels in spleen, skeletal muscle, small intestine, kidney and liver.
Target Synonyms
CCDC8; CCDC8_HUMAN; Coiled coil domain containing 8; Coiled-coil domain-containing protein 8; DKFZp564K0322; ENSMUSG00000041117; MGC72567
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