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The antibody against CCDC84 was raised in rabbit using the Recombinant Human Coiled-coil domain-containing protein 84 protein (1-200AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against CCDC84 was raised in rabbit using the Recombinant Human Coiled-coil domain-containing protein 84 protein (1-200AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human melanoma using CCDC84 Antibody at dilution of 1:100
| Cat.No | ADC-19453A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CCDC84 |
| Target Synonyms | CCD84_HUMAN antibody; Ccdc84 antibody; Coiled-coil domain-containing protein 84 antibody; DLNB14 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Coiled-coil domain-containing protein 84 protein (1-200AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86UT8 |
Uniprot Id
Q86UT8
Target Species
Human
Target Name
CENATAC
Target Full Name
Centrosomal AT-AC splicing factor
Target Function
Negative regulator of centrosome duplication. Constrains centriole number by modulating the degradation of the centrosome-duplication-associated protein SASS6 in an acetylation-dependent manner. SIRT1 deacetylates CENATAC in G1 phase, allowing for SASS6 accumulation on the centrosome and subsequent procentriole assembly. The CENATAC acetylation level is restored in mitosis by NAT10, promoting SASS6 proteasome degradation by facilitating SASS6 binding to APC/C E3 ubiquitin-protein ligase complex/FZR1.
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Target Synonyms
CCD84_HUMAN; Ccdc84; Coiled-coil domain-containing protein 84; DLNB14
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