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Rabbit anti-Human CCL22 Polyclonal Antibody

The antibody against CCL22 was raised in rabbit using the Recombinant Human C-C motif chemokine 22 protein (25-82AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

ADC-54543A

The antibody against CCL22 was raised in rabbit using the Recombinant Human C-C motif chemokine 22 protein (25-82AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-54543A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCCL22
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human C-C motif chemokine 22 protein (25-82AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO00626
Background Information
  • Uniprot Id

    O00626

  • Target Species

    Human

  • Target Name

    CCL22

  • Target Full Name

    C-C motif chemokine 22

  • Target Function

    May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Intercrine beta (chemokine CC) family

  • Target Tissue Specificity

    Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. I

  • Target Research Area

    Immunology

  • Target Synonyms

    A 152E5.1; ABCD 1; ABCD1; C C motif chemokine 22; CC chemokine STCP 1; CC chemokine STCP-1; ccl 22; Ccl22; CCL22_HUMAN; Chemokine (C C motif) ligand 22; DC/B CK; DCBCK; Macrophage-derived chemokine; MDC; MDC(1-69); MDC(7-69); MGC34554; SCYA22; Small inducible cytokine subfamily A (Cys Cys) member 22; Small inducible cytokine subfamily A; member 22; Small-inducible cytokine A22; STCP 1; STCP1; Stimulated T cell chemotactic protein 1 ; Stimulated T-cell chemotactic protein 1

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