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The antibody against CCNL1 was raised in rabbit using the Synthesized peptide derived from Human Cyclin-L1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
The antibody against CCNL1 was raised in rabbit using the Synthesized peptide derived from Human Cyclin-L1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
$297.00
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Cyclin-L1 antibody.
Western blot analysis of extracts from HepG2 cells, using Cyclin-L1 antibody.2
Western blot analysis of extracts from HeLa cells (Lane 2), A549 cells (Lane 3) and HepG2 cells (Lane 4), using Cyclin-L1 antiobdy. The lane on the left is treated with systhesized peptide.3
| Cat.No | ADC-42337A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CCNL1 |
| Target Synonyms | CCNL1 antibody; BM-001 antibody; UNQ530/PRO1073 antibody; Cyclin-L1 antibody; Cyclin-L antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Human Cyclin-L1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UK58 |
Uniprot Id
Q9UK58
Target Species
Human
Target Name
CCNL1
Target Full Name
Cyclin-L1
Target Function
Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs). Inhibited by the CDK-specific inhibitor CDKN1A/p21. May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC).
Target Subcellular Location
Nucleus speckle. Nucleus, nucleoplasm.
Target Protein Families
Cyclin family, Cyclin L subfamily
Target Tissue Specificity
Widely expressed. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC).
Target Synonyms
CCNL1; BM-001; UNQ530/PRO1073; Cyclin-L1; Cyclin-L
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