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The antibody against CCT7 was raised in rabbit using the Synthesized peptide derived from internal of Human CCT7. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against CCT7 was raised in rabbit using the Synthesized peptide derived from internal of Human CCT7. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from HeLa cells, using CCT7 antibody.
| Cat.No | ADC-40867A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CCT7 |
| Target Synonyms | N-terminally processed antibody; TCP-1-eta antibody; TCP1eta antibody; TCPH_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human CCT7. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99832 |
Uniprot Id
Q99832
Target Species
Human
Target Name
CCT7
Target Full Name
T-complex protein 1 subunit eta
Target Function
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. The TRiC complex plays a role in the folding of actin and tubulin.
Target Subcellular Location
Cytoplasm.
Target Protein Families
TCP-1 chaperonin family
Target Synonyms
CCT ETA; CCT-eta; CCT7; CCTETA; Ccth; Chaperonin containing t complex polypeptide 1 eta subunit; Chaperonin containing TCP1 subunit 7 (eta); Chaperonin containing TCP1 subunit 7; HIV 1 Nef interacting protein; HIV-1 Nef-interacting protein; Nip7 1; T complex protein 1 eta subunit; T-complex protein 1 subunit eta, N-terminally processed; TCP-1-eta; TCP1eta; TCPH_HUMAN
Target Background
This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.
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