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The antibody against CD109 was raised in rabbit using the Synthetic peptide from Human protein at AA range: 751-800 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against CD109 was raised in rabbit using the Synthetic peptide from Human protein at AA range: 751-800 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.
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Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
| Cat.No | ADC-13008A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CD109 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS | Purification Method | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide from Human protein at AA range: 751-800 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6YHK3 |
Uniprot Id
Q6YHK3
Target Species
Human
Target Name
CD109
Target Full Name
CD109 antigen
Target Function
Modulates negatively TGFB1 signaling in keratinocytes.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Target Protein Families
Protease inhibitor I39 (alpha-2-macroglobulin) family
Target Tissue Specificity
Widely expressed with high level in uterus, aorta, heart, lung, trachea, placenta and in fetal heart, kidney, liver, spleen and lung. Expressed by CD34(+) acute myeloid leukemia cell lines, T-cell lines, activated T-lymphoblasts, endothelial cells and act
Target Synonyms
150 KDa TGF beta 1 binding protein; 150 KDa TGF-beta-1-binding protein; 7D1; 8A3; Activated T cell marker CD109; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; CD 109; CD109; CD109 antigen; CD109_HUMAN; CPAMD7; DKFZp762L1111; E123; FLJ38569; FLJ41966; Gov system alloantigens on platelets; p180; Platelet specific Gov antigen; Platelet-specific Gov antigen; r150; RP11 525G3.1
Target Background
This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.
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