Rabbit anti-Human CD2 Polyclonal Antibody

The antibody against CD2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 235-351 of human CD2 (NP_001758.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-03731A

Number

Cat.No	ADA-03731A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CD2
Target Synonyms	T11; SRBC; LFA-2; CD2	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Jurkat, Molt-4	Application	ELISA, WB, IHC-P

Cat.No

ADA-03731A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CD2

Target Synonyms

T11; SRBC; LFA-2; CD2

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Jurkat, Molt-4

Application

ELISA, WB, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 235-351 of human CD2 (NP_001758.2).	Target Species	Human
Immunogen Sequence	TKRKKQRSRRNDEELETRAHRVATEERGRKPHQIPASTPQNPATSQHPPPPPGHRSQAPSHRPPPPGHRVQHQPQKRPPAPSGTQVHQQKGPPLPRPRVQPKPPHGAAENSLSPSSN	Uniprot ID	P06729

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 235-351 of human CD2 (NP_001758.2).

Target Species

Human

Immunogen Sequence

TKRKKQRSRRNDEELETRAHRVATEERGRKPHQIPASTPQNPATSQHPPPPPGHRSQAPSHRPPPPGHRVQHQPQKRPPAPSGTQVHQQKGPPLPRPRVQPKPPHGAAENSLSPSSN

Uniprot ID

P06729

Background Information

Uniprot Id

P06729
Target Species

Human
Target Name

CD2
Target Full Name

T-cell surface antigen CD2
Target Function

CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Target Subcellular Location

Cell membrane; Single-pass type I membrane protein.
Target Research Area

Cell Adhesion
Target Synonyms

CD 2; CD2; CD2 antigen (p50), sheep red blood cell receptor; CD2 antigen; CD2 molecule; CD2_HUMAN; Erythrocyte receptor; FLJ46032; LFA-2; LFA-3 receptor; LFA2; LFA3 receptor ; Ly-37; Lymphocyte function antigen 2; lymphocyte-function antigen-2; OTTHUMP00000024366; Rosette receptor; Sheep erythrocyte receptor; SRBC; T cell surface antigen CD2 ; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T-lymphocyte surface CD2 antigen; T11
Target Background

The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene.

Rabbit anti-Human CD2 Polyclonal Antibody

Specifications

Immunogen Information

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