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The antibody against CD48 was raised in mouse using the Recombinant Human CD48 protein (27-220AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG1, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF, FC.
The antibody against CD48 was raised in mouse using the Recombinant Human CD48 protein (27-220AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG1, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF, FC.
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Western Blot Positive WB detected in: Jurkat whole cell lysate, Raji whole cell lysate, Daudi whole cell lysate, Mouse liver tissue All lanes: CD48 antibody at 1:4000 Secondary Goat polyclonal to mouse IgG at 1/50000 dilution Predicted band size: 28, 20KDa Observed band size: 43 KDa Exposure time:5min
| Cat.No | ADC-56084A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Mouse | Target Name | CD48 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG1 | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB, FC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human CD48 protein (27-220AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P09326 |
Uniprot Id
P09326
Target Species
Human
Target Name
CD48
Target Full Name
CD48 antigen
Target Function
Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Target Research Area
Immunology
Target Synonyms
Antigen CD48; B cell membrane protein; B lymphocyte activation marker BLAST 1; B-cell activation marker; B-lymphocyte activation marker BLAST-1; BCM 1 surface antigen; BCM1; BCM1 surface antigen; BLAST 1; BLAST; BLAST1; CD 48; CD48; CD48 antigen (B cell membrane protein); CD48 antigen; CD48 molecule; CD48 protein; CD48_HUMAN; hCD48; Leucocyte antigen MEM 102; Leukocyte antigen MEM-102; mCD48; MEM 102; MEM-102; MEM102 ; Signaling lymphocytic activation molecule 2; SLAM family member 2; SLAMF 2; SLAMF2 ; TCT.1
Target Background
This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
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