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Rabbit anti-Human CD80 Monoclonal Antibody

The antibody against CD80 was raised in Rabbit using the recombinant protein of human CD80 as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-15314A

The antibody against CD80 was raised in Rabbit using the recombinant protein of human CD80 as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-15314A ClonalityMonoclonal
Host SpeciesRabbitTarget NameCD80
Target SynonymsB7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1; CD80FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse thymus, RajiApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant protein of human CD80.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP33681
Background Information
  • Uniprot Id

    P33681

  • Target Species

    Human

  • Target Name

    CD80

  • Target Full Name

    T-lymphocyte activation antigen CD80

  • Target Function

    Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.; (Microbial infection) Acts as a receptor for adenovirus subgroup B.

  • Target Subcellular Location

    Membrane; Single-pass type I membrane protein.

  • Target Tissue Specificity

    Expressed on activated B-cells, macrophages and dendritic cells.

  • Target Research Area

    Immunology

  • Target Synonyms

    CD80; CD28LG; CD28LG1; LAB7; T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD antigen CD80

  • Target Background

    The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.

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