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The antibody against CD80 was raised in Rabbit using the recombinant protein of human CD80 as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CD80 was raised in Rabbit using the recombinant protein of human CD80 as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-15314A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CD80 |
| Target Synonyms | B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1; CD80 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse thymus, Raji | Application | ELISA, WB |
| Immunogen Description | Recombinant protein of human CD80. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P33681 |
Uniprot Id
P33681
Target Species
Human
Target Name
CD80
Target Full Name
T-lymphocyte activation antigen CD80
Target Function
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.; (Microbial infection) Acts as a receptor for adenovirus subgroup B.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Expressed on activated B-cells, macrophages and dendritic cells.
Target Research Area
Immunology
Target Synonyms
CD80; CD28LG; CD28LG1; LAB7; T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD antigen CD80
Target Background
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
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