Rabbit anti-Human CD82 Monoclonal Antibody

The antibody against CD82 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 168-267 of human CD82 (P27701) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-15820A

Number

Cat.No	ADA-15820A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	CD82
Target Synonyms	R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27; CD82	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Jurkat, Raji	Application	ELISA, WB, IF/ICC, IHC-P

Cat.No

ADA-15820A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

CD82

Target Synonyms

R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27; CD82

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Jurkat, Raji

Application

ELISA, WB, IF/ICC, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 168-267 of human CD82 (P27701).	Target Species	Human
Immunogen Sequence	PEVTYPCSCEVKGEEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLSICLCRHVHSEDYSKVPKY	Uniprot ID	P27701

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 168-267 of human CD82 (P27701).

Target Species

Human

Immunogen Sequence

PEVTYPCSCEVKGEEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLSICLCRHVHSEDYSKVPKY

Uniprot ID

P27701

Background Information

Uniprot Id

P27701
Target Species

Human
Target Name

CD82
Target Full Name

CD82 antigen
Target Function

Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

Tetraspanin (TM4SF) family
Target Tissue Specificity

Lymphoid specific.
Target Synonyms

CD82; KAI1; SAR2; ST6; TSPAN27; CD82 antigen; C33 antigen; IA4; Inducible membrane protein R2; Metastasis suppressor Kangai-1; Suppressor of tumorigenicity 6 protein; Tetraspanin-27; Tspan-27; CD antigen CD82
Target Background

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Rabbit anti-Human CD82 Monoclonal Antibody

Specifications

Immunogen Information

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