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Rabbit anti-Human CDC14A Polyclonal Antibody

The antibody against CDC14A was raised in rabbit using the Synthesized peptide derived from Internal of Human CC14A. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-40731A

The antibody against CDC14A was raised in rabbit using the Synthesized peptide derived from Internal of Human CC14A. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-40731A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCDC14A
Target SynonymsCDC14A antibody; Dual specificity protein phosphatase CDC14A antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; CDC14 cell division cycle 14 homolog A antibodyFormLiquid
Species ReactivityHumanStorage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from Internal of Human CC14A.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9UNH5
Background Information
  • Uniprot Id

    Q9UNH5

  • Target Species

    Human

  • Target Name

    CDC14A

  • Target Full Name

    Dual specificity protein phosphatase CDC14A

  • Target Function

    Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis. Required for normal hearing.

  • Target Involvement

    Deafness, autosomal recessive, 105 (DFNB105)

  • Target Subcellular Location

    Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Cell projection, kinocilium. Cell projection, stereocilium.

  • Target Protein Families

    Protein-tyrosine phosphatase family, Non-receptor class CDC14 subfamily

  • Target Synonyms

    CDC14A; Dual specificity protein phosphatase CDC14A; EC 3.1.3.16; EC 3.1.3.48; CDC14 cell division cycle 14 homolog A

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