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The antibody against CDC14A was raised in rabbit using the Synthesized peptide derived from Internal of Human CC14A. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against CDC14A was raised in rabbit using the Synthesized peptide derived from Internal of Human CC14A. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
| Cat.No | ADC-40731A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CDC14A |
| Target Synonyms | CDC14A antibody; Dual specificity protein phosphatase CDC14A antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; CDC14 cell division cycle 14 homolog A antibody | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Internal of Human CC14A. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UNH5 |
Uniprot Id
Q9UNH5
Target Species
Human
Target Name
CDC14A
Target Full Name
Dual specificity protein phosphatase CDC14A
Target Function
Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis. Required for normal hearing.
Target Involvement
Deafness, autosomal recessive, 105 (DFNB105)
Target Subcellular Location
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Cell projection, kinocilium. Cell projection, stereocilium.
Target Protein Families
Protein-tyrosine phosphatase family, Non-receptor class CDC14 subfamily
Target Synonyms
CDC14A; Dual specificity protein phosphatase CDC14A; EC 3.1.3.16; EC 3.1.3.48; CDC14 cell division cycle 14 homolog A
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