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Rabbit anti-Human CDC40 Monoclonal Antibody

The antibody against CDC40 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDC40 (O60508) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-14273A

The antibody against CDC40 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDC40 (O60508) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-14273A ClonalityMonoclonal
Host SpeciesRabbitTarget NameCDC40
Target SynonymsEHB3; PCH15; PRP17; PRPF17; CDC40FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, HCT116, HepG2, Mouse brain, Mouse lung, Mouse spleen, Rat lungApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDC40 (O60508).Target SpeciesHuman
Immunogen SequenceMSAAIAALAASYGSGSGSESDSDSESSRCPLPAADSLMHLTKSPSSKPSLAVAVDSAPEVAVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRUniprot IDO60508
Background Information
  • Uniprot Id

    O60508

  • Target Species

    Human

  • Target Name

    CDC40

  • Target Full Name

    Pre-mRNA-processing factor 17

  • Target Function

    Required for pre-mRNA splicing as component of the activated spliceosome.

  • Target Subcellular Location

    Nucleus. Nucleus speckle.

  • Target Synonyms

    Cdc40; Cell division cycle 40; Cell division cycle 40 homolog; EH binding protein 3; EH-binding protein 3; Ehb3; hPRP17; Pre mRNA processing factor 17; Pre mRNA splicing factor 17; Pre-mRNA-processing factor 17; PRP17; PRP17 homolog; PRP17_HUMAN; PRPF17

  • Target Background

    Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.

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