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Rabbit anti-Human CDCA7 Polyclonal Antibody

The antibody against CDCA7 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CdcA7. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

ADC-33607A

The antibody against CDCA7 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CdcA7. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

$167.00

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Specifications


Cat.No ADC-33607A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCDCA7
Target SynonymsCDCA7 antibody; JPO1Cell division cycle-associated protein 7 antibody; Protein JPO1 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human CdcA7.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9BWT1
Background Information
  • Uniprot Id

    Q9BWT1

  • Target Species

    Human

  • Target Name

    CDCA7

  • Target Full Name

    Cell division cycle-associated protein 7

  • Target Function

    Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator.

  • Target Involvement

    Immunodeficiency-centromeric instability-facial anomalies syndrome 3 (ICF3)

  • Target Subcellular Location

    Nucleus. Cytoplasm. Note=Predominantly nuclear with some expression also seen in the cytoplasm. Predominantly cytoplasmic when phosphorylated at Thr-163.

  • Target Tissue Specificity

    Ubiquitous with higher level in thymus and small intestine. Overexpressed in a large number of tumors, in blood from patients with acute myelogenous leukemia (AML) and in chronic myelogenous leukemia (CML) blast crisis.

  • Target Synonyms

    CDCA7; JPO1Cell division cycle-associated protein 7; Protein JPO1

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