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The antibody against CDH15 was raised in rabbit using the Synthesized peptide derived from internal of Human CDH15. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against CDH15 was raised in rabbit using the Synthesized peptide derived from internal of Human CDH15. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from HepG2 cells and 293 cells, using CDH15 antibody.
| Cat.No | ADC-41705A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CDH15 |
| Target Synonyms | CDH15; CDH14; CDH3; Cadherin-15; Cadherin-14; Muscle cadherin; M-cadherin | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human CDH15. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P55291 |
Uniprot Id
P55291
Target Species
Human
Target Name
CDH15
Target Full Name
Cadherin-15
Target Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.
Target Involvement
Mental retardation, autosomal dominant 3 (MRD3)
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Expressed in the brain and cerebellum.
Target Synonyms
CDH15; CDH14; CDH3; Cadherin-15; Cadherin-14; Muscle cadherin; M-cadherin
Target Background
This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation.
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