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Rabbit anti-Human CDKL5 Polyclonal Antibody

The antibody against CDKL5 was raised in rabbit using the Recombinant Human Cyclin-dependent kinase-like 5 protein (790-921AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

ADC-02524A

The antibody against CDKL5 was raised in rabbit using the Recombinant Human Cyclin-dependent kinase-like 5 protein (790-921AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-02524A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCDKL5
FormLiquidSpecies ReactivityHuman, Rat
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Cyclin-dependent kinase-like 5 protein (790-921AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO76039
Background Information
  • Uniprot Id

    O76039

  • Target Species

    Human

  • Target Name

    CDKL5

  • Target Full Name

    Cyclin-dependent kinase-like 5

  • Target Function

    Mediates phosphorylation of MECP2. May regulate ciliogenesis.

  • Target Involvement

    Epileptic encephalopathy, early infantile, 2 (EIEE2)

  • Target Subcellular Location

    Nucleus. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

  • Target Protein Families

    Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily

  • Target Tissue Specificity

    Expressed in brain, lung, kidney, prostate, ovary, placenta, pancreas and testis.; [Isoform 2]: Predominant transcript in brain.

  • Target Synonyms

    Cdkl5; CDKL5_HUMAN; Cyclin dependent kinase 5 transcript; Cyclin-dependent kinase-like 5; EIEE2; ISSX; Serine/threonine kinase 9; Serine/threonine-protein kinase 9; Stk9

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