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The antibody against CDX1 was raised in rabbit using the Fusion protein of Human CDX1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against CDX1 was raised in rabbit using the Fusion protein of Human CDX1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-32086A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CDX1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human CDX1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P47902 |
Uniprot Id
P47902
Target Species
Human
Target Name
CDX1
Target Full Name
Homeobox protein CDX-1
Target Function
Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA.
Target Subcellular Location
Nucleus.
Target Protein Families
Caudal homeobox family
Target Tissue Specificity
Intestinal epithelium.
Target Synonyms
Caudal type homeo box transcription factor 1 ; Caudal type homeobox 1; Caudal type homeobox protein ; Caudal type homeobox protein CDX1; Caudal type homeobox transcription factor 1; Caudal-type homeobox protein 1; CDX1; CDX1_HUMAN; Homeobox protein CDX 1; Homeobox protein CDX-1; MGC116915; OTTHUMP00000160524
Target Background
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.
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