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Rabbit anti-Human CDY1 Polyclonal Antibody

The antibody against CDY1 was raised in rabbit using the Synthesized peptide derived from Internal of Human CDY1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-40761A

The antibody against CDY1 was raised in rabbit using the Synthesized peptide derived from Internal of Human CDY1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-40761A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCDY1
Target SynonymsCDY1 antibody; CDY1A; antibody; CDY1BTestis-specific chromodomain protein Y 1 antibody; EC 2.3.1.48 antibodyFormLiquid
Species ReactivityHumanStorage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from Internal of Human CDY1.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y6F8
Background Information
  • Uniprot Id

    Q9Y6F8

  • Target Species

    Human

  • Target Name

    CDY1

  • Target Full Name

    Testis-specific chromodomain protein Y 1

  • Target Function

    Has histone acetyltransferase activity, with a preference for histone H4.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Testis-specific. Detected in spermatids (at protein level).

  • Target Synonyms

    CDY1; CDY1A;; CDY1BTestis-specific chromodomain protein Y 1; EC 2.3.1.48

  • Target Background

    This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined.

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